The headline shouts out: “Scientists reverse the ageing process.” Researchers have found a way to protect a mouse’s DNA from the damage that comes with ageing, and they’re ready to test it on people. Dr. David Sinclair, from Harvard Medical School, and his colleagues have focused their research on an intriguing compound with anti-aging properties called NAD+. NAD+ is short for nicotinamide adenine dinucleotide. It’s been known that younger mice have more of it than older mice. Furthermore, the researchers found that when they boosted the NAD+ levels in older mice, they looked biologically, like much younger animals.

Dr. Sinclair put drops of NAD+ into the water of a group of mice and within a couple of hours their NAD+ levels started to rise. Within the first week, the scientists saw obvious age reversal in muscle and improvements in DNA repair.

“We can’t tell the difference between the tissues from an old mouse that is two years old versus a young mouse that is three to four months old,” Sinclair says.

Scientists reverse the ageing process: Can it work for humans?

In this case, unfortunately, a reversal of the ageing process in humans is unlikely. Human metabolism is different from that of rodents. Furthermore, our existence is unlike a mouse’s life in a cage. What is theoretically possible in the future remains unproven in humans and not ready for sale to the consumer.

History is replete with examples of cures that worked on mice but not in people. Multiple drugs, for instance, have been effective at targeting an Alzheimer’s-like disease in mice, yet they have failed in humans.

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